Siglec 10 antibody

WebApr 10, 2024 · The Siglec-Fc protein, a fusion protein combining Siglec with the Fc part of a human antibody, is a promising sialic acid-Siglec axis-targeted agent for cancer treatment … WebThe 5G6 monoclonal antibody specifically recognizes Sialic acid-binding Ig-like lectin 10 (Siglec-10). Siglec-10 is a type I transmembrane glycoprotein encoded by SIGLEC10 …

Development of Effective Siglec-9 Antibodies Against Cancer

WebWe offer Siglec-10 Antibodies for use in common research applications: Blockade of Receptor-ligand Interaction, ELISA, Flow Cytometry, Immunohistochemistry, … WebMar 21, 2024 · SIGLEC10 (Sialic Acid Binding Ig Like Lectin 10) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated … opening a youth group home in georgia https://fasanengarten.com

Anti Human Siglec-10 Antibody, clone 5G6 Bio-Rad

WebNov 29, 2024 · Summary. Siglec-9 is an immune checkpoint target and an immunoinhibitory receptor that can engage either sialic acid ligands or agonistic antibodies. Through Siglec … WebSiglec-10 is a lectin that specifically binds α-2,3- or α-2,6-linked sialic acid. It is a member of the Ig-superfamily and is expressed in monocytes, eosinophils, B cells, and a subset of NK … WebNov 29, 2024 · Summary. Siglec-9 is an immune checkpoint target and an immunoinhibitory receptor that can engage either sialic acid ligands or agonistic antibodies. Through Siglec-9 sialic acid interactions, activated immunoreceptor tyrosine-based inhibitory signaling of the immune cells can lead to unfavorable immunosuppression. opening a youth center costs

Siglec-8 Mast cells Eosinophils cells Allakos

Category:New insights on the early stages of HIV infection in the human body

Tags:Siglec 10 antibody

Siglec 10 antibody

Polyclonal Anti-SIGLEC10 Antibody - Atlas Antibodies

WebHigh-quality Siglec-10 proteins from ACROBiosystems. Various species and tags of Siglec-10 proteins. Minimal Batch-to-Batch Variation. Bulks in stock. Login Register. Bulk order. … WebSIGLEC10 antibody LS-C187565 is an unconjugated mouse monoclonal antibody to human SIGLEC10. Validated for Flow. Products. Research Areas. COVID-19. Resources. ... (NK) …

Siglec 10 antibody

Did you know?

WebSiglec-15, which selectively drives immunosuppression in the tumor microenvironment, has emerged as a viable therapeutic target. In a phase I trial of NC318, a Siglec-15 antibody, … WebAntibody information for antibodies HPA027093 and CAB025807 used in analysis of ENSG00000142512 / SIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) We use cookies …

Web1 day ago · Although the exact role of Siglec-1 in the context of HIV-1 infection is still an area of active ... more convenient antibody treatments. Apr 13, 2024. T cells: Vesicles strengthen immune response. WebAPC anti-human Siglec-10 Antibody. Human peripheral blood lymphocytes were stained with CD19 FITC and Siglec-10 (clone 5G6) APC (top) or mouse IgG1, κ APC isotype …

WebSIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. It preferentially binds to alpha2,3- or 2,6-linked sialic acid. The sialic acid recognition … WebJul 17, 2024 · Blocking the interaction between CD24 and Siglec-10 with a monoclonal antibody can robustly augment the phagocytosis of human tumors expressing CD24 . Other. CD24 on the surface of tumor cells can …

WebSiglec-10 Fc (Mouse IgFc) at 10 μg ml was incubated with anti-Siglec-10 antibodies and the Siglec-10Fc/antibody complexes were incubated with tumor cell lines and then washed. …

Like most but not all other Siglecs, Siglec-10 bears an ITIM (Immunoreceptor tyrosine-based inhibitory motif) within its cytoplasmic domain. Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to … See more Sialic acid-binding Ig-like lectin 10 is a protein that in humans is encoded by the SIGLEC10 gene. Siglec-G is often referred to as the murine paralog of human Siglec-10 See more SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor … See more • Li N, Zhang W, Wan T, et al. (2001). "Cloning and characterization of Siglec-10, a novel sialic acid binding member of the Ig superfamily, from human dendritic cells". J. Biol. Chem. 276 (30): 28106–12. doi:10.1074/jbc.M100467200. PMID 11358961. See more opening a zip fileWebJul 4, 2014 · Siglec-10 (human homolog of mouse Siglec-G) was detected on all B cells and also subsets of human leukocytes including eosinophils, monocytes and a minor … opening a zip file in teamsWebSIGLEC10 (MGC126774, PRO940, SIGLEC-10, SLG2) protein expression summary. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are … opening azithromycin capsulesWebPRO940 antibody, SIGLEC-10 antibody, SLG2 antibody, Siglecg antibody, SIGLEC10 antibody, slg2 antibody, pro940 antibody, siglec-10 antibody, sialic acid binding Ig like … opening a zip file windows 10WebFlow cytometric analysis of Siglec-10 expression on human peripheral blood lymphocytes. Human whole blood was stained with Alexa Fluor® 488 Mouse Anti-Human CD19 antibody (Cat. No. 555412) and either BD Horizon™ BV421 Mouse IgG1, κ Isotype Control (Cat. No. 562438; Left Plot) or BD Horizon BV421 Mouse Anti-Human Siglec-10 antibody (Cat. No. … opening a zip file with passwordWebIn one embodiment, an anti-Siglec-9 antibody has a KD of about 1×10 −7 M to about 1×10 −10 M, about 1×10 −8 M to about 1×10 −10 M, or about 1×10 −9 M to about 1×10 −11 M, … opening a zip file on windowsWebSIGLEC 10 antibody. Siglec G antibody. Siglec-like protein 2 antibody. SIGLEC10 antibody. Siglecg antibody. SLG2 antibody : Protein information supplied by UniProt . Accessories. … opening a zip file on ipad