Irf1 molecular weight
WebApr 16, 2002 · Molecular Function: RNA polymerase II transcription regulatory region sequence-specific DNA binding Source:ARUK-UCL. 1 publication. ... Note: MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. By similarity Keywords. Cellular component. #Cytoplasm; #Nucleus ... WebIRF1 Protein Molecular Weight & PI . The parameters have been computed for the following feature . FT CHAIN 1-325 Interferon regulatory factor 1. Molecular weight (Da) 36502.21 Theoretical pI . 5.22 Bulk Order of Recombinant IRF1 Protein . Please Leave Us a Message if you have any questions regarding bulk price quote of our products on the ...
Irf1 molecular weight
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WebPredicted molecular weight. 32.27 kDa . Stability and Storage. Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt. ... IRF1. Species. Human . Shipping. In general, proteins are provided as lyophilized powder/frozen liquid. They ... WebApr 15, 2024 · Recently, the therapeutic combination of atezolizumab and bevacizumab was widely used to treat advanced hepatocellular carcinoma (HCC). According to recent clinical trials, immune checkpoint inhibitors (ICIs) and molecular target agents are expected to be key therapeutic strategies in the future. Nonetheless, the mechanisms underlying …
WebMolecular function Cellular component: Biological process ... Interferon regulatory factor 1 is a protein that in humans is encoded by the IRF1 gene. ... Body weight: Normal Anxiety: Normal Neurological assessment: Normal Grip strength: Normal Hot plate: Normal Dysmorphology: WebSep 29, 2024 · Given that IRF-1 is well known to molecularly act downstream of IFN-γ signaling, we also subjected mice lacking IFN-γ to C. rodentium infection. However, compared to control mice, we observed no...
WebKO Validated STAR208P) and visualized on the ChemiDoc MP with 10 second exposure. Arrow points to IRF1 (molecular weight 47 kDa) Western blot analysis of IRF1 knockout HeLa and wild type HeLa (WT) whole cell lysates probed with (A) Rabbit anti IRF1 antibody (VPA00801STAR208P) and (B) hFAB rhodamine anti-tubulin primary antibody and … WebMar 21, 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer. Among its related pathways are Bacterial infections in CF airways and Overview of interferons-mediated signaling … HBB (Hemoglobin Subunit Beta) is a Protein Coding gene. Diseases associated with … Gene Ontology (GO) - Molecular Function for MET Gene. GO ID Qualified GO term … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … Complete information for IWS1 gene (Protein Coding), Interacts With SUPT6H, … PHGDH (Phosphoglycerate Dehydrogenase) is a Protein Coding gene. Diseases … CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases … IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. … CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … CDKN1B (Cyclin Dependent Kinase Inhibitor 1B) is a Protein Coding gene. Diseases …
WebDisruption of this signaling pathway by deletion of Irf1 or Stat1 protects mouse macrophages from TNF-α- and IFN-γ- induced cell death, as well as induced holopsia deletion in the absence of Irf1. Similarly, Stat1-/- mice were protected from TNF- and IFN-γ- induced death. Figure 4. TNF-α and IFN-γ induce JAK/STAT1/IRF1 signaling and PANoptosis
WebSep 19, 2010 · Blast analysis revealed that the porcine IRF1 gene has 85.7, 74.3 and 72.9% nucleotide identity with the corresponding human, mouse and rat IRF1 sequences, … smallwasteWebMar 29, 2024 · 1 INTRODUCTION. Glioblastoma, which is believed to be generated by progenitor or neuroglial stem cells, has the highest degree of malignancy among gliomas and the highest prevalence among brain tumors. 1, 2 Glioblastoma exhibits cell and nuclear rudimentary, microvascular proliferation, a high degree of cellularity, necrosis, and mitosis … smallwares menu bar ideasWebJan 15, 2024 · IRF1 are marked using red, and HSPA4, PDLIM4, and VDAC1 are illustrated in dark, common and light yellow, respectively; TCF7, SKP1, and PPP2CA appear as dark, … smallwares list for restaurant start uphildasenpai forumWebApr 4, 2024 · IRF-1 is an important signaling protein in the interferon pathway. It not only activates gene expression as a transcription factor, but may perpetuate disease by leading to a dysregulated epigenome. Data suggest that interferon regulatory factors 1 and 2 (IRF1 and IRF2) may serve as potential targets of therapy. smallwares portland oregonWebDec 16, 2024 · Background Interferon regulatory factor 1 (IRF1) is an important transcription factor that activates the type I interferon (IFN-I) response and plays a vital role in the antiviral immune response. Although IRF1 has been identified in several mammals, little information related to its function in canines has been described. Results In this study, canine IRF1 … smallwares taco bellWebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ). smallwares pdx