Dual specificity protein phosphatase 1

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August undefined, 2024

WebDual specificity phosphatase 1 (DUSP1), a negative regulator of the mitogen‑activated protein kinase (MAPK) signaling pathway, has anti‑inflammatory properties. In the … WebJun 25, 2024 · Our previous study demonstrated that dual-specificity protein phosphatase 1 (DUSP1) reduced hyperglycemia-mediated mitochondrial damage; however, its role in hyperglycemia-driven dysfunction of tubular cells is still not fully understood. In this study, we found that DUSP1 is reduced in human proximal tubular …

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WebJan 1, 2015 · Dual-specificity protein phosphatase 1 (DUSP1), known also as MAP kinase phosphatase 1 (MKP1), is implicated in metabolism and energy expenditure. Mice lacking DUSP1 are resistant to high-fat diet-induced obesity. However, the expression of DUSP1 has not been investigated in human obesity. In the current study, we compared … WebGlucocorticoids (GCs) potently inhibit pro-inflammatory responses and are widely used for the treatment of inflammatory diseases, such as allergies, autoimmune disorders, and asthma. Dual-specificity phosphatase 1 … i hope so are you

11072 - Gene ResultDUSP14 dual specificity phosphatase 14

WebApr 10, 2024 · dual specificity protein phosphatase CDC14A isoform 2 Download Models. Job ID Status Method Username Target Length Date (PST) Expiration Date … WebOct 21, 2024 · Encodes a protein tyrosine phosphatase Propyzamide-Hypersensitive 1 (PHS1). One of the mutant alleles, phs1-1, is hypersensitive to the microtubule-destabilizing drug propyzamide, suggesting that PHS1 may be involved in phosphorylation cascades that control the dynamics of cortical microtubules in plant cells. A second allele, phs1-3, is … WebMar 15, 2009 · Dual Specificity Phosphatase 1 / metabolism Dual Specificity Phosphatase 3 / metabolism Dual-Specificity Phosphatases / classification i hope she will get well soon

Entry - *618368 - DUAL-SPECIFICITY PHOSPHATASE 26; DUSP26

WebMar 21, 2024 · DUSP4 (Dual Specificity Phosphatase 4) is a Protein Coding gene. Diseases associated with DUSP4 include Ogden Syndrome.Among its related pathways are MyD88 dependent cascade initiated on endosome and RAF/MAP kinase cascade.Gene Ontology (GO) annotations related to this gene include phosphatase activity and … WebIntroduction. Dual-specificity phosphatase 2 (DUSP2) belongs to the nuclear type I DUSP family and its molecular function is to terminate the activity of mitogen-activated protein kinases (MAPKs) including ERK1/2, p38 MAPK, and JNK 1.Since DUSP2 is predominantly expressed in immune cells, most studies have focused on the role of DUSP2 in the … i hope she\\u0027s a fool i hope somebody got fired for that blunder

"WebLokareddy et al. (2013) obtained the 1.68-angstrom crystal structure of a catalytically inactive mutant (cys152 to ser) of DUSP26 lacking the first 60 N-terminal amino acids. … " - Dual specificity protein phosphatase 1

Dual specificity protein phosphatase 1

WebApr 7, 2024 · The primary structure of PPP5C can be mainly divided into three parts, the N-terminal tetrapeptide repeat (TPR) domain (residues 28–129), the middle phosphatase domain (residues 175–490), and the C-terminal α-J helix (residues 490–499) [4] (Fig. 1 A).The TPR domain contains 34 amino acids which exert the autoinhibition functions of … WebApr 7, 2024 · The primary structure of PPP5C can be mainly divided into three parts, the N-terminal tetrapeptide repeat (TPR) domain (residues 28–129), the middle phosphatase …

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WebThe bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the … WebJan 22, 2024 · Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism. Mitogen …

WebSep 27, 2024 · LSF2 is a dual specificity protein phosphatase that displays high activity toward para-nitrophenyl phosphate ... Dietrich H, Servatius A, Howells N, Cato AC, Lang R (2006) Dual specificity phosphatase 1 (DUSP1) regulates a subset of LPS-induced genes and protects mice from lethal endotoxin shock. J Exp Med 203(1):15–20. Web24 rows · Dual specificity phosphatase that dephosphorylates MAP kinase MAPK1/ERK2 on both 'Thr-183' and ...

WebDual specificity phosphatase 15 (Dusp15) represses myelin gene expression. Mag, Mbp, connexin 32 (Cx32), peripheral myelin protein 22 (Pmp22), and Srebp-1c mRNA levels … WebJan 1, 2024 · Download Citation On Jan 1, 2024, Ruibing Li and others published Interaction between dual specificity phosphatase-1 and cullin-1 attenuates alcohol …

WebJul 5, 2004 · PTHR47100:SF5 DUAL SPECIFICITY PROTEIN PHOSPHATASE PHS1 1 hit; PROSITE. View protein in PROSITE; PS00383 TYR_PHOSPHATASE_1 1 hit; PS50056 TYR_PHOSPHATASE_2 1 hit; PS50054 TYR_PHOSPHATASE_DUAL 1 hit; Pfam. View protein in Pfam; PF09192 Act-Frag_cataly 1 hit; PF00782 DSPc 1 hit; SMART.

WebDual specificity phosphatase 1 (DUSP1), a negative regulator of the mitogen‑activated protein kinase (MAPK) signaling pathway, has anti‑inflammatory properties. In the present study, the expression of DUSP1 was investigated in human OA fibroblast‑like synoviocytes (FLSs), human normal FLSs and OA FLSs pretreated with dexamethasone at the ... i hope she\u0027s a fool page numberWebMar 21, 2024 · dual specificity protein phosphatase 14, MAP kinase phosphatase 6, MKP-1-like protein tyrosine phosphatase, MKP-6, mitogen-activated protein kinase phosphatase 6. GeneRIFs: Gene References Into Functions. Bioinformatic studies showed that these two miRNAs target PTEN and DUSP14 tumor suppressor genes. Quantitative … i hope she\u0027ll be a fool pageWebLokareddy et al. (2013) obtained the 1.68-angstrom crystal structure of a catalytically inactive mutant (cys152 to ser) of DUSP26 lacking the first 60 N-terminal amino acids. DUSP26 adopted a closed conformation of the protein tyrosine phosphatase (PTP)-binding loop, resulting in a shallow active-site pocket and buried catalytic cysteine. i hope someone robs you and takes your fridgeWebThe structures of the compounds were identified mainly on the basis of MS and NMR data. Compound 1 inhibited VHR dual-specificity protein tyrosine phosphatase (DS-PTPase) activity in a dose-dependent manner, displaying an IC 50 value of 3.0 ± 0.2 μM. i hope she will recover soonWebPTHR45961:SF5 DUAL SPECIFICITY PROTEIN PHOSPHATASE 14 1 hit; PTHR45961 IP21249P 1 hit; PRINTS. PR01908 ADSPHPHTASE; PR01910 ADSPHPHTASEB; PROSITE. View protein in PROSITE; PS00383 TYR_PHOSPHATASE_1 1 hit; PS50056 TYR_PHOSPHATASE_2 1 hit; PS50054 TYR_PHOSPHATASE_DUAL 1 hit; Pfam. … i hope she\u0027s waiting for meWebDual specificity phosphatase 15 (Dusp15) represses myelin gene expression. Mag, Mbp, connexin 32 (Cx32), peripheral myelin protein 22 (Pmp22), and Srebp-1c mRNA levels were measured by quantitative RT-PCR in (a) RT4 Schwann cells, Dusp15 and Mag in (b) Primary Schwann cells treated with siRNA against Dusp15 and in (c and d) Dusp15-KO … i hope so commander for your sakeWebApr 10, 2024 · dual specificity protein phosphatase CDC14A isoform 2 Download Models. Job ID Status Method Username Target Length Date (PST) Expiration Date (PST) 505201: Complete: Structure prediction : sabdus: dual specificity protein ... 623: 10 Apr 2024: 25 May 2024: 1 . 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . 90 . 100 . ... i hope she stays there chords